1000L/H Stainless Steel SS304 Reverse Osmosis System For Pharmaceuticals Industry

1000L/H Stainless Steel SS304 Reverse Osmosis System For Pharmaceuticals Industry

I.Overview

The pharmaceutical industry requires extremely stringent water quality standards for Purified Water (PW), Water for Injection (WFI), cleaning water, and process water according to pharmacopeias such as USP, EP, and ChP.
Reverse Osmosis (RO) is the core purification technology, using high pressure to force water through semi-permeable membranes, effectively removing ions, microorganisms, organic matter, particulates, and endotoxins. RO plays a critical pre-treatment role in systems combined with EDI, UF, or mixed beds.

304 stainless steel, with its balanced corrosion resistance (especially against organic acids and weak alkalis in food environments), excellent hygiene performance, and good mechanical and processing properties, has become one of the most commonly used and reliable materials in food and beverage production equipment, conveyance pipelines, storage tanks, and water treatment (particularly clean water/process water) equipment.

2. Applications

• Purified Water (PW) generation

• Pre-treatment for Water for Injection (WFI)

• Cleaning water for medical device manufacturing

• Process water for biopharmaceutical production

• Water used in solid and liquid dosage manufacturing

• CIP/SIP water supply

3. Typical Process Flow

Raw Water → Multimedia Filter → Activated Carbon Filter → Chemical Dosing (Antiscalant/Biocide) → Cartridge Filter → RO Stage 1 → RO Stage 2 (optional) → EDI / Polishing Unit → Storage & Distribution System

Pharmaceutical water systems typically use Double Pass RO or RO + EDI configurations to ensure highly stable and compliant water quality.

4. Features & Advantages

1) Compliant with GMP & Pharmacopeial Standards

• Designed and manufactured according to GMP, ISPE, USP, and EP guidelines.

• Full validation documents available: DQ, IQ, OQ.

2) High Removal Efficiency

• RO membrane salt rejection ≥ 98%.

• Excellent removal of bacteria and endotoxins.

• Optional EDI enables continuous operation without chemical regeneration.

3) Sanitary Design

• 316L stainless steel pipelines with internal surface roughness ≤ Ra 0.4 μm.

• Dead-leg-free design and sanitary clamp fittings.

• Hot water sanitization (80°C) or ozone sanitization available.

4) Advanced Automation

• PLC + HMI control (Siemens/Mitsubishi/Schneider optional).

• Online monitoring: conductivity, pH, flow, pressure, temperature.

• Automatic flushing, scheduled cleaning, and multiple protection alarms.

5) Stable Water Quality

    Typical product water quality (depending on configuration):

• Conductivity: ≤ 1–10 μS/cm (meets Purified Water standards)

• Microorganisms: ≤ 100 CFU/mL

• Endotoxin: ≤ 0.25 EU/mL (with double RO or RO + UF)

5. System Components

• RO high-pressure pump (Grundfos/CNP)

• RO membrane elements (DOW / Hydranautics / Toray)

• Multimedia and activated carbon filters (SUS304 or FRP)

• Cartridge filters (5 μm / 1 μm)

• PLC control panel

• Sanitary-grade piping and valves

• Validation documentation package

6. Optional Pharmaceutical-Grade Modules

• Hot water circulation loop (80°C)

• Ozone generator with online monitoring

• UV sterilizers (254 nm / 185 nm)

• Online TOC analyzer

• Redundant dual-pump & dual-membrane design

VI.Here is a guideline for you to get a proper quotation

Tell us the raw water/source of water(tap water, well water, or sea water, etc)
Provide water analysis report(TDS , conductivity, or resistivity, etc)
Required production capacity( 5m³/H, 50m³/H,or 500m³/H, etc)
What's the pure water used for( industrial,Food and Beverage,or agriculture, etc )